Tacrolimus "Epione"

{
  "EntityId": "11277",
  "LastUpdated": "2026-07-17T00:36:42.754474\u002B02:00",
  "LastRevisedDate": {
    "Header": "Revisionsdato",
    "Value": "\u003Cdiv id=\u0022revisionsdato\u0022\u003E\u003Cp\u003E\u003Cspan class=\u0022dato\u0022\u003EMandag den 12. januar 2026\u003C/span\u003E. Priserne er dog g\u00E6ldende pr.\u003Cspan class=\u0022dato\u0022\u003Emandag den 6. juli 2026.\u003C/span\u003E\u003Cdiv class=\u0022smalltext\u0022\u003EDer kan forekomme forskelle mellem pr\u00E6paratbeskrivelsen og oplysningerne i produktresumeet og/eller indl\u00E6gssedlen. Det skyldes, at min.medicin.dk kan have suppleret L\u00E6gemiddelstyrelsens og producentens pr\u00E6paratinformationer med andre kilder. Min.medicin.dk har det fulde ansvar for pr\u00E6paratbeskrivelserne.\u003C/div\u003E\u003C/p\u003E\u003C/div\u003E"
  },
  "MedicineName": {
    "Header": "Pr\u00E6paratnavn",
    "Value": "Tacrolimus \u0022Epione\u0022"
  },
  "TradeNames": {
    "Header": "Handelsnavne",
    "Value": []
  },
  "Slug": "tacrolimus-epione",
  "CompanyName": {
    "Header": "Firmanavn",
    "Value": "Parallelimport"
  },
  "Usage": {
    "Header": "Bruges mod",
    "Value": "\u003Cdiv id=\u0022anvendelse\u0022\u003E\u003Cp\u003ETacrolimus \u0022Epione\u0022 er et hudmiddel, der anvendes til behandling af alvorlige tilf\u00E6lde af atopisk eksem, hvor anden behandling ikke har v\u00E6ret effektiv.\u003C/p\u003E\u003C/div\u003E"
  },
  "Dosage": {
    "Header": "Dosering",
    "Value": "\u003Cdiv id=\u0022doseringsforslag\u0022\u003E\u003Cp\u003EFindes som salve. \u003C/p\u003E\u003Cp\u003E\u003Cb\u003EVoksne og unge over 16 \u00E5r\u003C/b\u003E\u003C/p\u003E\u003Cul\u003E\u003Cli\u003ESalve sm\u00F8res p\u00E5 huden i et tyndt lag 2 gange i d\u00F8gnet \u003C/li\u003E\u003Cli\u003EHerefter forts\u00E6ttes eventuelt med salve med svagere styrke (0,03 %), indtil huden er helet. \u003C/li\u003E\u003C/ul\u003E\u003Cp\u003E\u003Cb\u003EVedligeholdelsesbehandling\u003C/b\u003E\u003C/p\u003E\u003Cul\u003E\u003Cli\u003ESalve sm\u00F8res p\u00E5 huden i et tyndt lag 1 gang i d\u00F8gnet 2 gange om ugen. \u003C/li\u003E\u003Cli\u003EVed eksemudbrud b\u00F8r behandling 2 gange daglig genindf\u00F8res. \u003C/li\u003E\u003Cli\u003EEfter 12 mdr. vurderes behovet for fortsat behandling af l\u00E6ge. \u003C/li\u003E\u003C/ul\u003E\u003Cbr/\u003E\u003C/div\u003E"
  },
  "HowToUse": {
    "Header": "S\u00E5dan tager du medicinen",
    "Value": {
      "KnuseDeleInformation": {
        "Header": "H\u00E5ndtering",
        "Value": null
      },
      "Termination": {
        "Header": "Stop af behandling",
        "Value": null
      },
      "MissedDose": {
        "Header": "Glemt medicin",
        "Value": null
      }
    }
  },
  "Precautions": {
    "Header": "Det skal du vide, n\u00E5r du tager medicinen",
    "Value": {
      "Contraindications": {
        "Header": "Hvorn\u00E5r m\u00E5 du ikke tage medicinen?",
        "Value": "\u003Cdiv id=\u0022boerikkeanvendes\u0022\u003E\u003Cul\u003E\u003Cli\u003ETacrolimus \u0022Epione\u0022 b\u00F8r ikke anvendes ved overf\u00F8lsomhed over for antibiotika af makrolidtypen (fx erythromycin) \u003C/li\u003E\u003Cli\u003EHvis der er infektion i huden b\u00F8r midlet ikke anvendes. \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
      },
      "RulesOfCaution": {
        "Header": "S\u00E6rlige advarsler",
        "Value": "\u003Cdiv id=\u0022saerligeadvarsler\u0022\u003E\u003Cul\u003E\u003Cli\u003EUnder behandlingen skal huden beskyttes mod sollys. \u003C/li\u003E\u003Cli\u003EBl\u00F8dg\u00F8rende creme b\u00F8r ikke benyttes p\u00E5 de behandlede hudomr\u00E5der fra 2 timer f\u00F8r til 2 timer efter p\u00E5sm\u00F8ring af midlet. \u003C/li\u003E\u003Cli\u003EKontakt med \u00F8jne og slimhinder b\u00F8r undg\u00E5s. \u003C/li\u003E\u003Cli\u003ESamtidig indtagelse af alkohol kan medf\u00F8re r\u00F8dme og hudirritation. \u003C/li\u003E\u003Cli\u003ETacrolimus \u0022Epione\u0022 b\u00F8r ikke anvendes, hvis du har en immundefekt eller er i behandling med l\u00E6gemidler, som neds\u00E6tter immunforsvaret, samt hvis du lider af en sygdom der beskadiger hudens barriere. \u003C/li\u003E\u003Cli\u003EPatienter, som udvikler bet\u00E6ndelse i lymfeknuderne, skal f\u00F8lges t\u00E6t af l\u00E6gen. \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
      },
      "Interactions": {
        "Header": "Brug af anden medicin",
        "Value": "\u003Cdiv id=\u0022brugafandenmedicin\u0022\u003E\u003Cp\u003EDet er vigtigt at informere l\u00E6gen om alle de l\u00E6gemidler, du tager.\u003C/p\u003E\u003Cul\u003E\u003Cli\u003EVed samtidig indtagelse af alkohol kan r\u00F8dme og hudirritation forekomme. \u003C/li\u003E\u003Cli\u003ETacrolimus \u0022Epione\u0022 b\u00F8r ikke anvendes, hvis du har en immundefekt eller er i behandling med l\u00E6gemidler, som neds\u00E6tter immunforsvaret. \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
      },
      "Pregnancy": {
        "Header": "Graviditet og fertilitet",
        "Value": "\u003Cdiv id=\u0022graviditet\u0022\u003EB\u00F8r ikke anvendes pga. manglende viden. Denne tekst afviger fra firmaets godkendte produktinformation (produktresum\u00E9).\u003C/div\u003E"
      },
      "Lactation": {
        "Header": "Amning",
        "Value": "\u003Cdiv id=\u0022amning\u0022\u003EKan om n\u00F8dvendigt anvendes. Denne tekst afviger fra firmaets godkendte produktinformation (produktresum\u00E9).\u003Cbr/\u003EB\u00F8r dog ikke anvendes p\u00E5 brystvorterne lige f\u00F8r amning.\u003C/div\u003E"
      },
      "Alchohol": {
        "Header": "Alkohol",
        "Value": "\u003Cdiv id=\u0022alkohol\u0022\u003E\u003Cp\u003E\u003Cp\u003E\u003Cb\u003EAlkohol: V\u00E6r forsigtig.\u003C/b\u003E\u003C/p\u003E\u003Cp\u003EDu b\u00F8r v\u00E6re forsigtig med at drikke alkohol, n\u00E5r du tager Tacrolimus \u0022Epione\u0022.\u003C/p\u003E\u003Cp\u003E\u003Cb\u003EHvad kan der ske, hvis jeg drikker alkohol?\u003C/b\u003E\u003C/p\u003E\u003Cp\u003EDet kan give pludselig r\u00F8dme og varme i huden.\u003C/p\u003E\u003C/p\u003E\u003C/div\u003E"
      },
      "BloodDonor": {
        "Header": "Bloddonor",
        "Value": "\u003Cdiv id=\u0022bloddonor\u0022\u003EM\u00E5 tappes. Om du kan tappes, afh\u00E6nger dog af din sygdom.\u003C/div\u003E"
      },
      "Doping": {
        "Header": "Doping",
        "Value": null
      },
      "Traffic": {
        "Header": "Trafik",
        "Value": null
      },
      "SchengenCertificate": {
        "Header": "Schengenattest (pillepas)",
        "Value": null
      },
      "ShelfLifeAndStorage": {
        "Header": "Holdbarhed og opbevaring",
        "Value": "\u003Cdiv id=\u0022Haandteringogholdbarhed\u0022\u003E\u003Cp\u003E\u003Cb\u003EHoldbarhed\u003C/b\u003E\u003C/p\u003E\u003Cp\u003E\u003Cb\u003EEfter \u00E5bning:\u003C/b\u003E Kan opbevares i h\u00F8jst 90 dage.\u003C/p\u003E\u003C/div\u003E"
      }
    }
  },
  "SideEffects": {
    "Header": "Bivirkninger",
    "Value": {
      "VeryCommon": {
        "Header": "Meget almindelige",
        "Comment": "Flere end 10 ud af 100 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Ubehag p\u00E5 det sted",
              "hvor medicinen er givet (fx i form af br\u00E6ndende fornemmelse eller kl\u00F8e)"
            ]
          }
        }
      },
      "Common": {
        "Header": "Almindelige",
        "Comment": "H\u00F8jst 10 ud af 100 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Smerter",
              "Bet\u00E6ndelse i huden",
              "\u00C6ndring i hudens f\u00F8lesans",
              "Bet\u00E6ndelse i h\u00E5rs\u00E6k",
              "R\u00F8dme"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Fork\u00F8lelsess\u00E5r",
              "Hudirritation",
              "Hududsl\u00E6t",
              "Pludselig r\u00F8dme og varmef\u00F8lelse (efter indtagelse af alkohol)"
            ]
          }
        }
      },
      "Uncommon": {
        "Header": "Ikke almindelige",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": []
          }
        }
      },
      "Rare": {
        "Header": "Sj\u00E6ldne",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": []
          }
        }
      },
      "VeryRare": {
        "Header": "Meget sj\u00E6ldne",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": []
          }
        }
      },
      "FrequencyNotKnown": {
        "Header": "Ikke kendt",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Hornhindebet\u00E6ndelse"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Leverpletter",
              "V\u00E6skeophobning i huden"
            ]
          }
        }
      }
    },
    "AdditionalSideEffectsText": "\u003Cp\u003EI meget sj\u00E6ldne tilf\u00E6lde er set hudkr\u00E6ft hos patienter, der er eller har v\u00E6ret i behandling med Tacrolimus \u0022Epione\u0022 salve. \u003C/p\u003E"
  },
  "ActiveSubstances": {
    "Header": "Virksomme stoffer",
    "Value": [
      {
        "Name": "Tacrolimus"
      }
    ]
  },
  "Products": {
    "Header": "Priser, pakninger og tilskud",
    "Value": [
      {
        "ProductNumber": "473978",
        "DisplayName": "Tacrolimus \u0022Epione\u0022 1 mg/g / 30 g",
        "Packaging": "30 g",
        "Price": 132.55,
        "PricePerUnit": 4.42,
        "TradeName": "Tacrolimus \u0022Epione\u0022",
        "PharmaceuticalForm": "Salve",
        "DrugStrength": "1 mg/g",
        "Dispensing": "Receptpligtigt, en udlevering",
        "Reimbursement": "Generelt medicintilskud",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "456179",
            "Slug": "tacrolimus-accord",
            "DisplayName": "Tacrolimus \u0022Accord\u0022 0,1 % / 30 g",
            "Price": 80.1,
            "PricePerUnit": 2.67,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "128187",
            "Slug": "tacrolimus-2care4",
            "DisplayName": "Tacrolimus \u00222care4\u0022 1 mg/g / 30 g",
            "Price": 86.55,
            "PricePerUnit": 2.88,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "450030",
            "Slug": "tacronova",
            "DisplayName": "Tacronova 1 mg/g / 30 g",
            "Price": 86.55,
            "PricePerUnit": 2.88,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "374211",
            "Slug": "takrozem",
            "DisplayName": "Takrozem 1 mg/g / 30 g",
            "Price": 86.7,
            "PricePerUnit": 2.89,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "084960",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 30 g (Orifarm)",
            "Price": 110.0,
            "PricePerUnit": 3.67,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "126884",
            "Slug": "tacrolimus-nordic-prime",
            "DisplayName": "Tacrolimus \u0022Nordic Prime\u0022 1 mg/g / 30 g",
            "Price": 160.4,
            "PricePerUnit": 5.35,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "159235",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 30 g (2care4)",
            "Price": 209.6,
            "PricePerUnit": 6.99,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "465578",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 30 g (Abacus)",
            "Price": 291.5,
            "PricePerUnit": 9.72,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "542984",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 30 g (Epione)",
            "Price": 322.25,
            "PricePerUnit": 10.74,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "473968",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 30 g",
            "Price": 389.75,
            "PricePerUnit": 12.99,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      },
      {
        "ProductNumber": "199999",
        "DisplayName": "Tacrolimus \u0022Epione\u0022 1 mg/g / 60 g",
        "Packaging": "60 g",
        "Price": 169.45,
        "PricePerUnit": 2.82,
        "TradeName": "Tacrolimus \u0022Epione\u0022",
        "PharmaceuticalForm": "Salve",
        "DrugStrength": "1 mg/g",
        "Dispensing": "Receptpligtigt, en udlevering",
        "Reimbursement": "Generelt medicintilskud",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "400733",
            "Slug": "tacrolimus-accord",
            "DisplayName": "Tacrolimus \u0022Accord\u0022 0,1 % / 60 g",
            "Price": 157.8,
            "PricePerUnit": 2.63,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "383726",
            "Slug": "tacrolimus-2care4",
            "DisplayName": "Tacrolimus \u00222care4\u0022 1 mg/g / 60 g",
            "Price": 188.6,
            "PricePerUnit": 3.14,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "536750",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 60 g (Abacus)",
            "Price": 324.1,
            "PricePerUnit": 5.4,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "389145",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 60 g (2care4)",
            "Price": 345.55,
            "PricePerUnit": 5.76,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "582309",
            "Slug": "tacrolimus-nordic-prime",
            "DisplayName": "Tacrolimus \u0022Nordic Prime\u0022 1 mg/g / 60 g",
            "Price": 414.2,
            "PricePerUnit": 6.9,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "052891",
            "Slug": "protopic",
            "DisplayName": "Protopic 0,1% / 60 g (Epione)",
            "Price": 533.35,
            "PricePerUnit": 8.89,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      }
    ]
  },
  "Excipients": {
    "Header": "Hj\u00E6lpestoffer",
    "Value": [
      "\u003Cdiv id=\u0022hjaelpestoffer\u0022\u003E\u003Cp\u003E\u003Cb\u003EAndre:\u003C/b\u003E\u003C/p\u003E\u003Cspan class=\u0022navn\u0022\u003EParaffin, hvid bl\u00F8d\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Esalve 1 mg/g\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EBivoks\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Esalve 1 mg/g\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EParaffin\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Esalve 1 mg/g\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EParaffinolie\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Esalve 1 mg/g\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EPropylencarbonat\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Esalve 1 mg/g\u003C/span\u003E\u003C/div\u003E"
    ]
  },
  "PharmacologicalEffect": {
    "Header": "S\u00E5dan virker medicinen",
    "Value": "\u003Cdiv id=\u0022virkning\u0022\u003E\u003Cp\u003EVirker ved at undertrykke kroppens immunforsvar og d\u00E6mpe v\u00E6vsreaktionen (inflammationen) ved atopisk eksem.\u003C/p\u003E\u003C/div\u003E"
  },
  "Reimbursement": {
    "Header": "Tilskud",
    "Value": null
  }
}