Nobligan®

{
  "EntityId": "1609",
  "LastUpdated": "2026-07-17T00:35:31.985095\u002B02:00",
  "LastRevisedDate": {
    "Header": "Revisionsdato",
    "Value": "\u003Cdiv id=\u0022revisionsdato\u0022\u003E\u003Cp\u003E\u003Cspan class=\u0022dato\u0022\u003ETorsdag den 18. juni 2026\u003C/span\u003E. Priserne er dog g\u00E6ldende pr.\u003Cspan class=\u0022dato\u0022\u003Emandag den 6. juli 2026.\u003C/span\u003E\u003Cdiv class=\u0022smalltext\u0022\u003EDer kan forekomme forskelle mellem pr\u00E6paratbeskrivelsen og oplysningerne i produktresumeet og/eller indl\u00E6gssedlen. Det skyldes, at min.medicin.dk kan have suppleret L\u00E6gemiddelstyrelsens og producentens pr\u00E6paratinformationer med andre kilder. Min.medicin.dk har det fulde ansvar for pr\u00E6paratbeskrivelserne.\u003C/div\u003E\u003C/p\u003E\u003C/div\u003E"
  },
  "MedicineName": {
    "Header": "Pr\u00E6paratnavn",
    "Value": "Nobligan\u00AE"
  },
  "TradeNames": {
    "Header": "Handelsnavne",
    "Value": [
      "Nobligan Retard"
    ]
  },
  "Slug": "nobligan",
  "CompanyName": {
    "Header": "Firmanavn",
    "Value": "Gr\u00FCnenthal"
  },
  "Usage": {
    "Header": "Bruges mod",
    "Value": "\u003Cdiv id=\u0022anvendelse\u0022\u003E\u003Cp\u003ENobligan\u00AE er et smertestillende middel.\u003C/p\u003E\u003Cp\u003ENobligan\u00AE anvendes ved moderate til st\u00E6rke smerter. \u003Cbr/\u003E\u003Ci\u003EDepottabletter\u003C/i\u003E er ikke egnede til behandling af akutte smerter, men anvendes ved kroniske smerter.\u003C/p\u003E\u003C/div\u003E"
  },
  "Dosage": {
    "Header": "Dosering",
    "Value": "\u003Cdiv id=\u0022doseringsforslag\u0022\u003E\u003Cp\u003EFindes som depottabletter og kapsler.\u003C/p\u003E\u003Cp\u003E\u003Cbr/\u003E\u003Cb\u003EKapsler\u003C/b\u003E\u003C/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cb\u003EVoksne og b\u00F8rn over 12 \u00E5r\u003C/b\u003E\u003Ci\u003E.\u003C/i\u003E S\u00E6dvanligvis 50-100 mg 3-4 gange i d\u00F8gnet. \u003C/li\u003E\u003C/ul\u003E\u003Cp\u003E\u003Cbr/\u003E\u003Cb\u003EDepottabletter\u003C/b\u003E\u003C/p\u003E\u003Cul\u003E\u003Cli\u003E\u003Cb\u003EVoksne og b\u00F8rn over 12 \u00E5r.\u003C/b\u003E S\u00E6dvanligvis 100 mg 2 gange i d\u00F8gnet. \u003C/li\u003E\u003Cli\u003EDosis kan \u00F8ges efter behov til 150-200 mg 2 gange i d\u00F8gnet. \u003C/li\u003E\u003C/ul\u003E\u003Cp\u003E\u003Cb\u003EBem\u00E6rk:\u003C/b\u003E\u003C/p\u003E\u003Cul\u003E\u003Cli\u003EDosis skal neds\u00E6ttes ved d\u00E5rligt fungerende nyrer (GFR 0-20 ml/min)\u003C/li\u003E\u003C/ul\u003E\u003Cbr/\u003E\u003C/div\u003E"
  },
  "HowToUse": {
    "Header": "S\u00E5dan tager du medicinen",
    "Value": {
      "KnuseDeleInformation": {
        "Header": "H\u00E5ndtering",
        "Value": "\u003Cdiv id=\u0022KnuseDeleInformation\u0022\u003E\u003Cp\u003E\u003Cdiv\u003E\u003Ch4\u003E\u003Cspan data-drugid=\u002228101462391\u0022\u003E\u003Cb\u003EH\u00E5rde kapsler 50 mg\u003C/b\u003E\u003C/span\u003E\u003Cbr/\u003E\u003C/h4\u003E\u003Cbr/\u003E\u003Cb\u003EMad og drikke\u003C/b\u003E\u003Cdiv\u003ETages med et glas vand\u003Cbr/\u003EKan tages med eller uden mad\u003Cbr/\u003EIndholdet kan kommes p\u00E5 bl\u00F8d mad, fx yoghurt eller \u00E6blemos\u003C/div\u003E\u003Cbr/\u003E\u003Cb\u003EKnusning/\u00E5bning\u003C/b\u003E\u003Cdiv\u003EKan \u00E5bnes\u003C/div\u003E\u003Cbr/\u003E\u003Cb\u003EAdministration\u003C/b\u003E\u003Cdiv\u003EIndholdet kan opsl\u00E6mmes i vand\u003C/div\u003E\u003C/div\u003E\u003C/p\u003E\u003Cp\u003E\u003Cdiv\u003E\u003Ch4\u003E\u003Cspan data-drugid=\u002228101854296\u0022\u003E\u003Cb\u003EDepottabletter 100 mg, 150 mg og 200 mg\u003C/b\u003E\u003C/span\u003E\u003Cbr/\u003E\u003C/h4\u003E\u003Cbr/\u003E\u003Cb\u003EMad og drikke\u003C/b\u003E\u003Cdiv\u003EKan tages med eller uden mad\u003C/div\u003E\u003Cbr/\u003E\u003Cb\u003EKnusning/\u00E5bning\u003C/b\u003E\u003Cdiv\u003EM\u00E5 ikke knuses\u003C/div\u003E\u003Cbr/\u003E\u003Cb\u003EAdministration\u003C/b\u003E\u003Cdiv\u003ESynkes hele med et glas vand\u003Cbr/\u003EM\u00E5 ikke tygges\u003C/div\u003E\u003C/div\u003E\u003C/p\u003E\u003C/div\u003E"
      },
      "Termination": {
        "Header": "Stop af behandling",
        "Value": "\u003Cdiv id=\u0022seponering\u0022\u003E\u003Cp\u003EHvis du skal stoppe behandling med Nobligan\u00AE efter l\u00E6ngere tids brug, b\u00F8r det foreg\u00E5 langsomt og gerne over mange uger for at undg\u00E5 bivirkninger. \u003C/p\u003E\u003C/div\u003E"
      },
      "MissedDose": {
        "Header": "Glemt medicin",
        "Value": null
      }
    }
  },
  "Precautions": {
    "Header": "Det skal du vide, n\u00E5r du tager medicinen",
    "Value": {
      "Contraindications": {
        "Header": "Hvorn\u00E5r m\u00E5 du ikke tage medicinen?",
        "Value": null
      },
      "RulesOfCaution": {
        "Header": "S\u00E6rlige advarsler",
        "Value": "\u003Cdiv id=\u0022saerligeadvarsler\u0022\u003E\u003Cul\u003E\u003Cli\u003EAlkohol forst\u00E6rker midlets sl\u00F8vende virkning. \u003C/li\u003E\u003Cli\u003EForsigtighed ved forh\u00F8jet tryk i hjernen. \u003C/li\u003E\u003Cli\u003EB\u00F8r undg\u00E5s ved sv\u00E6r overf\u00F8lsomhed for st\u00E6rke smertestillende midler, som fx morfin. \u003C/li\u003E\u003Cli\u003EForsigtighed ved s\u00F8vnapn\u00F8 (korte perioder med pauser i vejrtr\u00E6kningen under s\u00F8vn). Dosis skal muligvis s\u00E6nkes.\u003C/li\u003E\u003Cli\u003EMidlet kan medf\u00F8re b\u00E5de psykisk og fysisk \u003Cb\u003Eafh\u00E6ngighed.\u003C/b\u003E Er afh\u00E6ngighed opst\u00E5et, vil pludseligt oph\u00F8r med indtagelse af midlet udl\u00F8se abstinenssymptomer, der viser sig ved almen utilpashed, gaben, t\u00E5refl\u00E5d, snue, nysen, svedudbrud, g\u00E5sehud, diarr\u00E9, hovedpine, rysten p\u00E5 arme og ben og evt. kramper. Desuden kan der opst\u00E5 en st\u00E6rk trang til atter at indtage stoffet. Ved oph\u00F8r af behandlingen skal dosis derfor nedtrappes gradvist for at undg\u00E5 abstinenser. \u003C/li\u003E\u003Cli\u003EDer kan opst\u00E5 \u003Cb\u003Etolerans\u003C/b\u003E ved brug over l\u00E6ngere tid. Det betyder, at man har behov for h\u00F8jere og h\u00F8jere doser for at behandle de samme smerter. \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
      },
      "Interactions": {
        "Header": "Brug af anden medicin",
        "Value": "\u003Cdiv id=\u0022brugafandenmedicin\u0022\u003E\u003Cp\u003EDet er vigtigt at informere l\u00E6gen om alle de l\u00E6gemidler, du tager.\u003C/p\u003E\u003Cul\u003E\u003Cli\u003ECarbamazepin (epilepsimiddel) neds\u00E6tter virkningen af Nobligan\u00AE. \u003C/li\u003E\u003Cli\u003ENobligan\u00AE kan \u00F8ge den sl\u00F8vende virkning af sovemidler, midler mod depression eller epilepsi og mod psykoser. \u003C/li\u003E\u003Cli\u003ENobligan\u00AE kan \u00F8ge virkningen af blodfortyndende midler. \u003C/li\u003E\u003Cli\u003ENobligan\u00AE m\u00E5 ikke anvendes til patienter, som er i behandling med MAO-h\u00E6mmere (midler mod depression eller Parkinsons sygdom). Der skal g\u00E5 mindst 14 dage mellem behandling med Nobligan\u00AE og MAO-h\u00E6mmere. \u003C/li\u003E\u003Cli\u003ESamtidig brug af visse midler mod depression (fx SSRI-midler og SNRI-midler), visse smertestillende midler (fx fentanyl) og visse midler mod migr\u00E6ne (triptaner) giver risiko for \u003Cb\u003Eserotoninsyndrom\u003C/b\u003E (bl.a. feber, stivhed, rysten, muskelkramper og \u00E6ndret mental tilstand). Serotoninsyndrom kan v\u00E6re alvorligt og kr\u00E6ver hurtig l\u00E6gehj\u00E6lp. \u003C/li\u003E\u003Cli\u003ESamtidig brug af visse l\u00E6gemidler (fx visse midler mod depression, antihistaminer, midler mod psykoser, muskelafslappende midler eller midler mod Parkinsons sygdom) kan medf\u00F8re svimmelhed, konfusion, hukommelsesbesv\u00E6r eller forstoppelse. \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
      },
      "Pregnancy": {
        "Header": "Graviditet og fertilitet",
        "Value": "\u003Cdiv id=\u0022graviditet\u0022\u003EM\u00E5 kun anvendes under visse foruds\u00E6tninger. Denne tekst afviger fra firmaets godkendte produktinformation (produktresum\u00E9).\u003Cp\u003EDer er en let \u00F8get risiko for misdannelser hos barnet. B\u00F8r ikke anvendes i de sidste 2 uger f\u00F8r forventet f\u00F8dsel p\u00E5 grund af risiko for nedsat vejrtr\u00E6kning hos barnet. Anvendes kun i s\u00E6rlige tilf\u00E6lde efter aftale med l\u00E6gen.\u003C/p\u003E\u003C/div\u003E"
      },
      "Lactation": {
        "Header": "Amning",
        "Value": "\u003Cdiv id=\u0022amning\u0022\u003EKan om n\u00F8dvendigt anvendes.\u003C/div\u003E"
      },
      "Alchohol": {
        "Header": "Alkohol",
        "Value": "\u003Cdiv id=\u0022alkohol\u0022\u003E\u003Cp\u003E\u003Cp\u003E\u003Cb\u003EAlkohol b\u00F8r undg\u00E5s.\u003C/b\u003E\u003C/p\u003E\u003Cp\u003EDu b\u00F8r ikke drikke alkohol, n\u00E5r du tager Nobligan\u00AE.\u003C/p\u003E\u003Cp\u003E\u003Cb\u003EHvad kan der ske, hvis jeg drikker alkohol?\u003C/b\u003E\u003C/p\u003E\u003Cp\u003EDen sl\u00F8vende effekt af Nobligan\u00AE bliver forst\u00E6rket.\u003C/p\u003E\u003C/p\u003E\u003C/div\u003E"
      },
      "BloodDonor": {
        "Header": "Bloddonor",
        "Value": "\u003Cdiv id=\u0022bloddonor\u0022\u003EM\u00E5 ikke tappes. 2 d\u00F8gns karant\u00E6ne.\u003Cbr/\u003E\u003Cp\u003EVed indtag p\u00E5 grund af akutte smerter (fx akut l\u00E6ndehold) kan donor tappes efter karant\u00E6ne p\u00E5 2 d\u00F8gn. \u003C/p\u003E\u003Cp\u003EVed fast dagligt forbrug m\u00E5 donor ikke tappes. Donors tappeegnethed skal vurderes af l\u00E6ge.\u003C/p\u003E\u003Cbr/\u003EIngen karant\u00E6ne ved tapning af plasma til fraktionering.\u003C/div\u003E"
      },
      "Doping": {
        "Header": "Doping",
        "Value": null
      },
      "Traffic": {
        "Header": "Trafik",
        "Value": "\u003Cdiv id=\u0022trafik\u0022\u003E\u003Cp\u003ENobligan\u00AE kan virke sl\u00F8vende og kan derfor p\u00E5virke din evne til at f\u00E6rdes sikkert i trafikken eller betjene maskiner. \u003C/p\u003E\u003Cp\u003ETal med din l\u00E6ge.\u003Cbr/\u003E\u003C/p\u003E\u003C/div\u003E"
      },
      "SchengenCertificate": {
        "Header": "Schengenattest (pillepas)",
        "Value": "Ved dette pr\u00E6parat kan man f\u00E5 pillepas til rejser i Schengen-lande. Se \u003Ca href=\u0022https://www.apoteket.dk/sundhed-og-sygdom/sol-og-rejse/skal-du-have-pillepas-med-paa-rejsen\u0022 title=\u0022Skal du have pillepas med p\u00E5 rejsen?\u0022\u003ESkal du have pillepas med p\u00E5 rejsen?\u003C/a\u003E"
      },
      "ShelfLifeAndStorage": {
        "Header": "Holdbarhed og opbevaring",
        "Value": null
      }
    }
  },
  "SideEffects": {
    "Header": "Bivirkninger",
    "Value": {
      "VeryCommon": {
        "Header": "Meget almindelige",
        "Comment": "Flere end 10 ud af 100 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Svimmelhed"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Kvalme"
            ]
          }
        }
      },
      "Common": {
        "Header": "Almindelige",
        "Comment": "H\u00F8jst 10 ud af 100 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Forstoppelse",
              "Mundt\u00F8rhed",
              "Opkastning",
              "Tr\u00E6thed",
              "Hovedpine",
              "D\u00F8sighed",
              "\u00D8get svedtendens"
            ]
          }
        }
      },
      "Uncommon": {
        "Header": "Ikke almindelige",
        "Comment": "H\u00F8jst 1 ud af 100 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Blodtryksfald n\u00E5r man rejser sig",
              "Kredsl\u00F8bschok"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Hjertebanken",
              "Hurtig hjerterytme",
              "Diarr\u00E9",
              "Oppustethed",
              "Sure opst\u00F8d",
              "N\u00E6ldefeber",
              "Hudkl\u00F8e",
              "Hududsl\u00E6t"
            ]
          }
        }
      },
      "Rare": {
        "Header": "Sj\u00E6ldne",
        "Comment": "H\u00F8jst 1 ud af 1.000 personer f\u00E5r bivirkningen.",
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Langsom puls",
              "Sl\u00F8ret syn",
              "Allergisk h\u00E6velse i ansigtet samt mundhulen og strubehovedet",
              "Anafylaktisk chok - en akut alvorlig allergisk tilstand",
              "Kramper",
              "Muskelsvaghed",
              "Koordinationsbesv\u00E6r",
              "Rysten",
              "\u00C6ndring i hudens f\u00F8lesans",
              "Angst",
              "Delirium - en tilstand med konfusion og p\u00E5virkning af syns- og h\u00F8reindtryk",
              "Forvirring",
              "Hallucinationer",
              "Hum\u00F8rsvingninger",
              "Problemer med tankevirksomhed og hukommelse",
              "Talebesv\u00E6r",
              "Manglende vandladning",
              "Muskelsammentr\u00E6kninger i luftr\u00F8rene",
              "Nedsat vejrtr\u00E6kning",
              "\u00C5nden\u00F8d",
              "Besvimelsesanfald",
              "Forh\u00F8jet blodtryk"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Forst\u00F8rrede pupiller",
              "Sm\u00E5 pupiller",
              "Appetitforstyrrelser",
              "Mareridt",
              "S\u00F8vnforstyrrelser",
              "Smertefuld vandladning"
            ]
          }
        }
      },
      "VeryRare": {
        "Header": "Meget sj\u00E6ldne",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": []
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": []
          }
        }
      },
      "FrequencyNotKnown": {
        "Header": "Ikke kendt",
        "Comment": null,
        "Value": {
          "SeriousAdverseReactions": {
            "Header": "Potentielt alvorlige bivirkninger",
            "Value": [
              "Abstinenser *",
              "Tilv\u00E6nning",
              "Serotoninsyndrom",
              "D\u00E5rligt fungerende binyrebark ***",
              "For lidt natrium i blodet",
              "Lavt blodsukker",
              "Afh\u00E6ngighed af midlet **"
            ]
          },
          "NonSeriousAdverseReactions": {
            "Header": "Oftest ikke alvorlige bivirkninger",
            "Value": [
              "Hikke",
              "\u00D8get f\u00F8lsomhed for smerter"
            ]
          }
        }
      }
    },
    "AdditionalSideEffectsText": "\u003Cp\u003E* Kan opst\u00E5 hvis du pludselig afbryder behandlingen.\u003C/p\u003E\u003Cp\u003E**Alkoholmisbrug, tobaksrygning og psykisk sygdom (fx sv\u00E6r depression, angst og personlighedsforstyrrelser) eller samtidig brug af psykofarmaka (fx sovemedicin) kan \u00F8ge risikoen for afh\u00E6ngighed. R\u00E5df\u00F8ring med en misbrugsspecialist kan overvejes. \u003C/p\u003E\u003Cp\u003E***Nobligan\u00AE kan for\u00E5rsage forbig\u00E5ende binyrebark-mangel, som kan kr\u00E6ve behandling med binyrebarkhormoner. Symptomerne p\u00E5 akut eller kronisk binyrebark-mangel kan v\u00E6re sv\u00E6re mavesmerter, kvalme og opkastning, lavt blodtryk, voldsom tr\u00E6thed, nedsat appetit og v\u00E6gttab.\u003C/p\u003E\u003Ch4\u003EPraktiske erfaringer\u003C/h4\u003E\u003Cp\u003EAnvendelse af opioider kan medf\u00F8re st\u00F8rre f\u00F8lsomhed for smerter, og at nye og mere diffuse smerter opst\u00E5r, is\u00E6r efter l\u00E6ngerevarende brug og/eller h\u00F8je doser. Denne st\u00F8rre smertef\u00F8lsomhed kan afhj\u00E6lpes ved at neds\u00E6tte dosis eller skifte til anden form for opioid.\u003C/p\u003E"
  },
  "ActiveSubstances": {
    "Header": "Virksomme stoffer",
    "Value": [
      {
        "Name": "Tramadol"
      }
    ]
  },
  "Products": {
    "Header": "Priser, pakninger og tilskud",
    "Value": [
      {
        "ProductNumber": "559062",
        "DisplayName": "Nobligan 50 mg / 100 stk.",
        "Packaging": "100 stk.",
        "Price": 112.75,
        "PricePerUnit": 1.13,
        "TradeName": "Nobligan",
        "PharmaceuticalForm": "Kapsler, h\u00E5rde",
        "DrugStrength": "50 mg",
        "Dispensing": "Kopieringspligtigt",
        "Reimbursement": "Generelt klausuleret medicintilskud, recept",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "094332",
            "Slug": "tramadol-actavis",
            "DisplayName": "Tramadol \u0022Actavis\u0022 50 mg / 100 stk. (blister)",
            "Price": 42.35,
            "PricePerUnit": 0.42,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "399074",
            "Slug": "tradolan",
            "DisplayName": "Tradolan 50 mg / 100 stk. (blister)",
            "Price": 47.3,
            "PricePerUnit": 0.47,
            "SubstitutionPriceGroup": "B",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "389901",
            "Slug": "dolol",
            "DisplayName": "Dolol 50 mg / 100 stk. (blister)",
            "Price": 54.25,
            "PricePerUnit": 0.54,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "556095",
            "Slug": "tramadol-krka",
            "DisplayName": "Tramadol \u0022Krka\u0022 50 mg / 100 stk. (blister)",
            "Price": 109.85,
            "PricePerUnit": 1.1,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "011215",
            "Slug": "tadol",
            "DisplayName": "Tadol 50 mg / 100 stk. (blister)",
            "Price": 111.15,
            "PricePerUnit": 1.11,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      },
      {
        "ProductNumber": "469932",
        "DisplayName": "Nobligan Retard 100 mg / 100 stk. (blister)",
        "Packaging": "100 stk. (blister)",
        "Price": 181.05,
        "PricePerUnit": 1.81,
        "TradeName": "Nobligan Retard",
        "PharmaceuticalForm": "Depottabletter",
        "DrugStrength": "100 mg",
        "Dispensing": "Kopieringspligtigt",
        "Reimbursement": "Generelt klausuleret medicintilskud, recept",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "548977",
            "Slug": "tramadol-retard-hexal",
            "DisplayName": "Tramadol Retard \u0022Hexal\u0022 100 mg / 100 stk. (blister)",
            "Price": 53.95,
            "PricePerUnit": 0.54,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "087892",
            "Slug": "dolatramyl",
            "DisplayName": "Dolatramyl 100 mg / 100 stk.",
            "Price": 55.35,
            "PricePerUnit": 0.55,
            "SubstitutionPriceGroup": "B",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "091842",
            "Slug": "tramadol-retard-actavis",
            "DisplayName": "Tramadol Retard \u0022Actavis\u0022 100 mg / 100 stk. (blister)",
            "Price": 55.4,
            "PricePerUnit": 0.55,
            "SubstitutionPriceGroup": "B",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "040092",
            "Slug": "tramadol-krka",
            "DisplayName": "Tramadol \u0022Krka\u0022 100 mg / 100 stk. (blister)",
            "Price": 55.5,
            "PricePerUnit": 0.56,
            "SubstitutionPriceGroup": "B",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "568829",
            "Slug": "tradolan-retard",
            "DisplayName": "Tradolan Retard 100 mg / 100 stk. (blister)",
            "Price": 115.05,
            "PricePerUnit": 1.15,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      },
      {
        "ProductNumber": "469874",
        "DisplayName": "Nobligan Retard 150 mg / 100 stk. (blister)",
        "Packaging": "100 stk. (blister)",
        "Price": 316.8,
        "PricePerUnit": 3.17,
        "TradeName": "Nobligan Retard",
        "PharmaceuticalForm": "Depottabletter",
        "DrugStrength": "150 mg",
        "Dispensing": "Kopieringspligtigt",
        "Reimbursement": "Generelt klausuleret medicintilskud, recept",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "532883",
            "Slug": "dolatramyl",
            "DisplayName": "Dolatramyl 150 mg / 100 stk.",
            "Price": 71.1,
            "PricePerUnit": 0.71,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "091860",
            "Slug": "tramadol-retard-actavis",
            "DisplayName": "Tramadol Retard \u0022Actavis\u0022 150 mg / 100 stk. (blister)",
            "Price": 72.0,
            "PricePerUnit": 0.72,
            "SubstitutionPriceGroup": "B",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "589302",
            "Slug": "tramadol-krka",
            "DisplayName": "Tramadol \u0022Krka\u0022 150 mg / 100 stk. (blister)",
            "Price": 93.05,
            "PricePerUnit": 0.93,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "590908",
            "Slug": "tradolan-retard",
            "DisplayName": "Tradolan Retard 150 mg / 100 stk. (blister)",
            "Price": 150.0,
            "PricePerUnit": 1.5,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      },
      {
        "ProductNumber": "469817",
        "DisplayName": "Nobligan Retard 200 mg / 100 stk. (blister)",
        "Packaging": "100 stk. (blister)",
        "Price": 345.6,
        "PricePerUnit": 3.46,
        "TradeName": "Nobligan Retard",
        "PharmaceuticalForm": "Depottabletter",
        "DrugStrength": "200 mg",
        "Dispensing": "Kopieringspligtigt",
        "Reimbursement": "Generelt klausuleret medicintilskud, recept",
        "ExpirationDate": null,
        "IsVariablePrice": false,
        "Substitutes": [
          {
            "ProductNumber": "440431",
            "Slug": "tramadol-krka",
            "DisplayName": "Tramadol \u0022Krka\u0022 200 mg / 100 stk. (blister)",
            "Price": 64.55,
            "PricePerUnit": 0.65,
            "SubstitutionPriceGroup": "A",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "062682",
            "Slug": "tradolan-retard",
            "DisplayName": "Tradolan Retard 200 mg / 100 stk. (blister)",
            "Price": 99.5,
            "PricePerUnit": 0.99,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "091878",
            "Slug": "tramadol-retard-actavis",
            "DisplayName": "Tramadol Retard \u0022Actavis\u0022 200 mg / 100 stk. (blister)",
            "Price": 100.75,
            "PricePerUnit": 1.01,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          },
          {
            "ProductNumber": "431840",
            "Slug": "dolatramyl",
            "DisplayName": "Dolatramyl 200 mg / 100 stk. (blister)",
            "Price": 111.15,
            "PricePerUnit": 1.11,
            "SubstitutionPriceGroup": "C",
            "ExpirationDate": null,
            "IsVariablePrice": false
          }
        ]
      }
    ]
  },
  "Excipients": {
    "Header": "Hj\u00E6lpestoffer",
    "Value": [
      "\u003Cdiv id=\u0022hjaelpestoffer\u0022\u003E\u003Cp\u003E\u003Cb\u003EFarve:\u003C/b\u003E\u003C/p\u003E\u003Cspan class=\u0022navn\u0022\u003EJernoxider og jernhydroxider (E172)\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EQuinolingult (E104)\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003ETitandioxid (E171)\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cp\u003E\u003Cb\u003EAndre:\u003C/b\u003E\u003C/p\u003E\u003Cspan class=\u0022navn\u0022\u003EGelatine\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EHypromellose\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EKolloid silica\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003ELactose\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EMacrogoler\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EMagnesiumstearat\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EMikrokrystallinsk cellulose\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003ENatriumlaurylsulfat\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003ENatriumstivelsesglykolat\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Eh\u00E5rde kapsler 50 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003EPropylenglycol (E-1520)\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003Cbr/\u003E\u003Cspan class=\u0022navn\u0022\u003ETalcum (E553b)\u003C/span\u003E : \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 100 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 150 mg\u003C/span\u003E, \u003Cspan class=\u0022dispenseringsformogstyrke\u0022\u003Edepottabletter 200 mg\u003C/span\u003E\u003C/div\u003E"
    ]
  },
  "PharmacologicalEffect": {
    "Header": "S\u00E5dan virker medicinen",
    "Value": "\u003Cdiv id=\u0022virkning\u0022\u003E\u003Cul\u003E\u003Cli\u003EVirker smertestillende ved at p\u00E5virke de omr\u00E5der i hjernen, der registrerer smerte. \u003C/li\u003E\u003Cli\u003EHalveringstiden i blodet (T\u00BD) er 5-6 timer. \u003C/li\u003E\u003Cli\u003EFor depotkapsler (Dolol Retard UNO og Tramadolhydrochlorid \u00222care4\u0022) er halveringstiden i blodet lidt l\u00E6ngere (6-9 timer). \u003C/li\u003E\u003C/ul\u003E\u003C/div\u003E"
  },
  "Reimbursement": {
    "Header": "Tilskud",
    "Value": "\u003Cdiv id=\u0022tilskud\u0022\u003E\u003Cp\u003EHvis du opfylder visse betingelser, kan du normalt f\u00E5 tilskud. Sp\u00F8rg din l\u00E6ge.\u003C/p\u003E\u003C/div\u003E"
  }
}